31,403 research outputs found

    Tackling socially determined dental inequalities: ethical aspects of Childsmile, the national child oral health demonstration programme in Scotland

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    Many ethical issues are posed by public health interventions, including whether they ought to be aimed at improving health across society or reducing specific health inequalities, whether they should be targeted or universal and the issue of which targeting criteria ought to be used. Although abstract theorising about these issues can be useful, it is the application of ethical theory to real cases which will ultimately be of benefit in decision-making. To this end, this paper will analyse the ethical issues involved in Childsmile, a national oral health demonstration programme in Scotland that aims to improve the oral health of the nation’s children and reduce dental inequalities through a combination of targeted and universal interventions. With Scotland’s level of dental caries among the worst in the Western world, Childsmile represents perhaps the largest programme of work aimed at combating oral health inequalities in the UK. The areas of ethical interest include several contrasting themes: reducing health inequalities and improving health; universal and targeted interventions; political values and evidence base; prevention and treatment; and underlying all of these, justice and utility

    Optimal Conditions for Kinetic Study of Succinate Dehydrogenase in Rat Liver

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    Succinate dehydrogenase (SDH) commonly is assayed as a marker enzyme for mitochondrial activity. The literature presents numerous conditions for conducting this assay due to the fact that, it has been difficult to get sufficient reduction of the acceptor dye, 2,3,5-triphenyl-2H-tetrazolium chloride (TTC). This study was undertaken to optimize the SDH-catalyzed reduction of TTC dye by evaluation of a greater range of molor ratios of TTC to succinate and by further evaluation of additives reported as beneficial. Improvement in enzyme specific activity was achieved by liver perfusion via the left cardiac ventricle with homogenizing solution. Increase in TTC from 1 to 10 mM and further increase to 20 mM resulted in major improvement in color production. The greatest improvement in apparent activity was achieved by addition of 1 mM phenozine methosulfate, a hydrogen transfer mediator. Use of CaCI₂. EDTA, Triton X-100, NaN₃ and KCN was not beneficial. The above modifications of the SDH assay resulted in greater sensitivity, the conduct of a greater number of assays with less tissue and the sacrifice of fewer animals

    Intending to be ethical: An examination of consumer choice in sweatshop avoidance

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    While much research in ethical consumption has focused on contexts such as food, this research explores ethical consumer decision-making in the context of intention to avoid sweatshop apparel. This research seeks to deepen the Theory of Planned Behavior with respect to the motivation and volitional stages underlying behavior. The findings of the research, based on 794 consumers, are novel and support an enriched framework which reveals that the role of attitude, subjective norm and perceived behavioral control are mediated by desire, intention and plan. The findings have implications for research seeking to address the ‘intention-behavior’ gap

    Characteristics of an anechoic chamber for fan noise testing

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    Acoustical and mechanical design features of NASA Lewis Research Center's engine fan noise facility are described. Acoustic evaluation of the chamber, which is lined with an array of stepped wedges, is described. Results from the evaluation in terms of cut-off frequency and non-anechoic areas near the walls are detailed. Fan models are electrically driven to 20,600 RPM in either the inlet mode or exhaust mode to facilitate study of both fore and aft fan noise. Inlet noise characteristics of the first fan tested are discussed and compared to full-scale levels. Turbulence properties of the inlet flow and acoustic results are compared with and without a turbulence reducing screen over the fan inlet

    Experimental evaluation of shockless supercritical airfoils in cascade

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    Surface Mach number distributions, total pressure loss coefficients, and schlieren images of the flow are presented over a range of inlet Mach numbers and air angles. Several different trailing edge geometries were tested. At design conditions a leading edge separation bubble was observed resulting in higher losses than anticipated. The minimum losses were obtained at a negative incidence condition in which the flow was accelerating over most of the supercritical region. Relatively minor differences in losses were measured with the different trailing edge geometries studied

    Unsteady pressure measurements on a biconvex airfoil in a transonic oscillating cascade

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    Flush-mounted dynamic pressure transducers were installed on the center airfoil of a transonic oscillating cascade to measure the unsteady aerodynamic response as nine airfroils were simultaneously driven to provide 1.2 deg of pitching motion about the midchord. Initial tests were performed at an incidence and angle of 0 deg and A Mach number of 0.65 in order to obtain results in a shock-free compressible flowfield. Subsequent tests were performed at an incidence angle of 7 deg and Mach number of 0.8 in order to observe the surface pressures with an oscillating shock near the leading edge of the airfoil. Results are presented for interblade phase angles of 90 and -90 deg and at blade oscillatory frequencies of 200 and 500 Hz (semi-chord reduced frequencies up to about 0.5 at a Mach number of 0.8). Results from the zero-incidence cascade are compared with a classical unsteady flat-plate analysis. Flow visualization results depicting the shock motion on the airfoils in the high-incidence cascade are discussed. The airfoil pressure data are tabulated

    A spectrum of carbon dioxide from 800 to 5500 cm-1

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    An atlas of CO2 lines obtained from long path length samples at 296 K is presented. Many of the line centers are marked and their positions tabulated

    The Local Effects of Cosmological Variations in Physical 'Constants' and Scalar Fields I. Spherically Symmetric Spacetimes

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    We apply the method of matched asymptotic expansions to analyse whether cosmological variations in physical `constants' and scalar fields are detectable, locally, on the surface of local gravitationally bound systems such as planets and stars, or inside virialised systems like galaxies and clusters. We assume spherical symmetry and derive a sufficient condition for the local time variation of the scalar fields that drive varying constants to track the cosmological one. We calculate a number of specific examples in detail by matching the Schwarzschild spacetime to spherically symmetric inhomogeneous Tolman-Bondi metrics in an intermediate region by rigorously construction matched asymptotic expansions on cosmological and local astronomical scales which overlap in an intermediate domain. We conclude that, independent of the details of the scalar-field theory describing the varying `constant', the condition for cosmological variations to be measured locally is almost always satisfied in physically realistic situations. The proof of this statement provides a rigorous justification for using terrestrial experiments and solar system observations to constrain or detect any cosmological time variations in the traditional `constants' of Nature.Comment: 30 pages, 3 figures; corrected typo
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